Dat FarCry 3, Skyrim + DLC, or Blops II.
These are grim times indeed. I don't want anything to take the place of Halo 4 as my go-to multiplayer game, but I don't want to get FarCry solely for singleplayer. Skyrim's always good fun, but I've completed the story a time or two already.
Oh, and XCOM, thanks to a Kotaku user who posted something about below. The comment was pretty cool and made me want to experience the game in a similar way.